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Mol Cell 82(12):22152227

Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41

The 'take it whenever' advice that works for metformin fails here

Their development as useful therapeutics, however, has been limited by physiochemical properties that make them susceptible to metabolic degradation and impermeable to gut and blood-brain barriers

Ethics statement The animal study was approved by Animal Ethics Committee of the Experimental Animal Center of South China Agricultural University